Anti-RAET1C monoclonal antibody, clone DY2 Functional Grade

Antibody Isotype

IgG2b

Clone

DY2

Species Reactivity

Mouse

Immunogen

The details of the immunogen for this antibody are not available. corresponding to Mouse Raet1c.Database link: O08604

Conjugate

Application Notes

Flow Cyt: 0.125μg/10⁶ cells.

Alternative Names

RAET1C; retinoic acid early transcript gamma; retinoic acid early-inducible protein 1-gamma; RAE-1-gamma; Rae-1 alpha; RAE-1gamma;

Entrez Gene ID

UniProt ID

Antigen Description

Retinoic acid early-inducible protein 1-gamma (Raet1c) belongs to the RAE-1 family of NKG2D ligands. They are induced by retinoic acid and expressed predominantly in embryonic brain during early embryogenesis. Detected at high levels in 7, 11 and 14-day-old embryos but not in 18-day-old embryos. Very low levels are detected in adults, however the presence of retinoic acid or certain disease conditions (such as tumors) can induce up-regulation of this protein at the cell surface.

Pathway

Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem.