Anti-Radial Glial Cell Marker-2 monoclonal antibody (DMABT-H21806)

Mouse anti-Rat Radial Glial Cell Marker-2 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Clone
SD3
Species Reactivity
Rat
Immunogen
Embryonic rat brain
Conjugate
Unconjugated

Target


Alternative Names
RC2; Mouse Anti-Radial Glial Cell Marker-2 Monoclonal Antibody; Anti-Radial Glial Cell Marker-2 Monoclonal Antibody; Radial Glial Cell Marker-2 Monoclonal Antibody Mouse Anti-Radial Glial Cell Marker-2 MAb; Anti-Radial Glial Cell Marker-2 MAb; Radial Glia

Product Background


Antigen Description
The antigen recognized bySD3is robust, allowing aldehyde fixation appropriate to high resolution light and electron microscopic analyses. From the neural tube stage of fetal development the antibody delineates throughout the central nervous system a subpopulation of neuroepithelial cells which have a radial bipolar morphology. SD3also recognizes monopolar cell forms in the spinal cord and the cerebellum as early as E15, and in the dentate gyrus of the hippocampal formation from the day of birth. Monopolar forms in the cerebellum are inferred to be progenitors of Bergmann glia. The robustness of the antigen recognized bySD3makes this probe a valuable tool to study the morphological transformations of the bipolar radial glia during their mitotic turnover. It also provides a sensitive stain for the study of the organization and the histogenetic role of the overall radial fiber system.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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