Anti-RPS27A polyclonal antibody

Species Reactivity

Human

Immunogen

RPS27A (AAH01392, 1 a.a. ~ 156 a.a) full-length recombinant protein with GST tag. The sequence is MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN IQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRE CPSDECGAGVFMASHFDRHYCGKCCLTYCFNKPEDK

Conjugate

Unconjugated

Alternative Names

RPS27A; ribosomal protein S27a; UBC; S27A; CEP80; UBA80; HEL112; UBCEP1; UBCEP80; ubiquitin-40S ribosomal protein S27a; ubiquitin C; ubiquitin-CEP80; 40S ribosomal protein S27a; epididymis luminal protein 112; ubiquitin and ribosomal protein S27a; ubiquit

Entrez Gene ID

6233

UniProt ID

B2RDW1

Antigen Description

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq, Sep 2008]

Pathway

APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc2 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc2 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Activated NOTCH1 Transmits Signal to the Nucleus.

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More