Anti-RPL14 monoclonal antibody, clone FQS23412

Antibody Isotype

IgG

Clone

FQS23412

Species Reactivity

Mouse; Rat; Human

Immunogen

Recombinant fragment within Human RPL14 aa 1-150. The exact sequence is proprietary.Database link: P50914

Conjugate

Application Notes

IHC-P: 1/100 - 1/250; WB: 1/1000 - 1/10000.

Alternative Names

RPL14; ribosomal protein L14; 60S ribosomal protein L14; CAG ISL 7; CTG B33; hRL14; L14; RL14; CTG-B33; CAG-ISL-7; MGC88594;

Entrez Gene ID

UniProt ID

Antigen Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Pathway

Cap-dependent Translation Initiation, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Elongation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Eukaryotic Translation Termination, organism-specific biosystem; Formation of a pool of free 4S subunits, organism-specific biosystem.