RP2 (NP_008846, 251 a.a. ~ 350 a.a) partial recombinant protein with GST tag. The sequence is RKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEV CQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death
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