Anti-RIT2 monoclonal antibody, clone 2H3

Antibody Isotype

IgG1

Clone

2H3

Species Reactivity

Human

Immunogen

Recombinant full length protein of Human RIT2 produced in HEK293T cells (NP_002921).

Conjugate

Application Notes

WB: 1/2000; Flow Cyt: 1/100; ICC/IF: 1/100;

Alternative Names

RIT2; Ras-like without CAAX 2; Ric (Drosophila) like, expressed in neurons , RIN; GTP-binding protein Rit2; RIBA; GTP-binding protein Roc2; Ric-like, expressed in neurons; ras-like without CAAX protein 2; ras-like protein expressed in neurons; RIN; ROC2;

Entrez Gene ID

UniProt ID

Antigen Description

Binds and exchanges GTP and GDP.

Pathway

NGF signalling via TRKA from the plasma membrane, organism-specific biosystem; Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signalling by NGF, organism-specific biosystem; Signalling to ERKs, organism-specific biosystem; Signalling to p38 via RIT and RIN, organism-specific biosystem; Trk receptor signaling mediated by the MAPK pathway, organism-specific biosystem;