Specifications
Species Reactivity
Rat; Human
Immunogen
Synthetic peptide corresponding to the third GTP unit of human TC10
Applications
Application Notes
WB: 1/1000 - 1/10000; ICC/IF: 1/250 - 1/500.
Target
Alternative Names
RHOQ; ras homolog family member Q; ARHQ, ras homolog gene family, member Q , RAS like, family 7, member A , RASL7A; rho-related GTP-binding protein RhoQ; TC10; ras-like protein TC10; RAS-like, family 7, member A; ras homolog gene family, member Q; ras-l
Product Background
Antigen Description
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
Pathway
Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem; Insulin-mediated glucose transport, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Citations
Publication ()
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COA
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