Anti-REPS2 monoclonal antibody, clone 5D3

Antibody Isotype

IgM

Clone

5D3

Species Reactivity

Human; Mouse

Immunogen

REPS2 (NP_004717, 66 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

REPS2; RALBP1 associated Eps domain containing 2; ralBP1-associated Eps domain-containing protein 2; POB1; partner of RalBP1; RALBP1-interacting protein 2; partner of Ral-binding protein 1;

Entrez Gene ID

UniProt ID

Antigen Description

The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

EGFR1 Signaling Pathway, organism-specific biosystem;