Anti-RBBP9 monoclonal antibody (DCABH-638)
Mouse anti-Human RBBP9 monoclonal antibody for WB, ICC/IF
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Recombinant full length Human RBBP9 produced in HEK293T cells (NP_006597).
WB: 1/500; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
RBBP9; retinoblastoma binding protein 9; putative hydrolase RBBP9; Bog; RBBP-9; RBBP-10
RBBP9 (Retinoblastoma Binding Protein 9) is a Protein Coding gene. Diseases associated with RBBP9 include retinoblastoma and corneal dystrophy, posterior polymorphous, 1. GO annotations related to this gene include hydrolase activity. The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. Putative hydrolase RBBP9 is an enzyme that in humans is encoded by the RBBP9 gene. The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. The function about RBBP9 antigen include hydrolase activity.
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Kim, SH; Lewis, JJ; et al. Overexpression of cyclin D1 is associated with poor prognosis in extremity soft-tissue sarcomas. CLINICAL CANCER RESEARCH 4:2377-2382(1998).
Frassanito, MA; Cusmai, A; et al. Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis. BLOOD 97:483-489(2001).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.