Anti-RBBP9 monoclonal antibody (DCABH-638)

Mouse anti-Human RBBP9 monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5F2
Species Reactivity
Human
Immunogen
Recombinant full length Human RBBP9 produced in HEK293T cells (NP_006597).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RBBP9; retinoblastoma binding protein 9; putative hydrolase RBBP9; Bog; RBBP-9; RBBP-10
Entrez Gene ID
UniProt ID

Product Background


Gene summary
RBBP9 (Retinoblastoma Binding Protein 9) is a Protein Coding gene. Diseases associated with RBBP9 include retinoblastoma and corneal dystrophy, posterior polymorphous, 1. GO annotations related to this gene include hydrolase activity. The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.
Antigen Description
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. Putative hydrolase RBBP9 is an enzyme that in humans is encoded by the RBBP9 gene. The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. The function about RBBP9 antigen include hydrolase activity.

Citations


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References


BARTKOVA, J; LUKAS, J; et al. THE PRAD-1 CYCLIN D1 ONCOGENE PRODUCT ACCUMULATES ABERRANTLY IN A SUBSET OF COLORECTAL CARCINOMAS. INTERNATIONAL JOURNAL OF CANCER 58:568-573(1994).
ARAMANT, RB; SEILER, MJ; et al. HUMAN EMBRYONIC RETINAL CELL TRANSPLANTS IN ATHYMIC IMMUNODEFICIENT RAT HOSTS. CELL TRANSPLANTATION 3:461-474(1994).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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