Recombinant human RAPSN protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-353 aa of BC004196
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:1000
General Notes
This product (Catalog No. DPABH-09241) is a rabbit-derived polyclonal antibody raised against human RAPSN, targeting the amino acid region 1–353 of the protein. This antibody exhibits cross-reactivity with Human RAPSN from mouse. It has been affinity purified by Protein A. This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]. DPABH-09241 is suitable for use in Western blot (WB) (1:500–1:1,000) application. DPABH-09241 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
43 kDa postsynaptic protein; CMS1D; CMS1E; RAPSN; RAPsyn; RING finger protein 205; RNF205
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