Anti-RAB12 polyclonal antibody (DPABH-20974)

Rabbit Anti-Human RAB12 (aa 124-187) polyclonal antibody for IHC-P, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
antigen sequence: ITKKETFDDL PKWMKMIDKY ASEDAELLLV GNKLDCETDR EITRQQGEKF AQQITGMRFC EASA, corresponding to internal sequence amino acids 124-187 of Human RAB12.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1/50 - 1/200. ICC/IF: 1 - 4 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RAB12; RAB12, member RAS oncogene family; ras-related protein Rab-12; putative Ras-related protein Rab-12
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
RAB12 (RAB12, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB12 include pustulosis of palm and sole. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RAB10. The function about RAB12 antigen include GDP binding; GTP binding.

Citations


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References


Iida, H; Wang, L; et al. Identification of rab12 as a secretory granule-associated small GTP-binding protein in atrial myocytes. CIRCULATION RESEARCH 78:343-347(1996).
OLKKONEN, VM; DUPREE, P; et al. MOLECULAR-CLONING AND SUBCELLULAR-LOCALIZATION OF 3 GTP-BINDING PROTEINS OF THE RAB SUBFAMILY. JOURNAL OF CELL SCIENCE 106:1249-1261(1993).

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