Anti-Parasite Apoptotic marker Monoclonal antibody (DMAB9287)
Mouse Anti-Parasite Apoptotic marker Monoclonal antibody for IHC
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Apoptotic marker from Caenorhabditis elegans.
Apoptosis is the fundamental process necessary for eliminating damaged or unwanted cells. Alterations in the apoptotic pathway appear to be key events in cancer development and progression. The aim of the study was to determine the p53, Bcl-2 and Bax expressions in lung cancer, taking into account histological heterogeneity and the adjacent bronchial resection margin. Tissue specimens from 60 histopathologically verified lung cancer specimens and 12 bronchial stumps were evaluated. The presence of the studied markers was revealed by immunocytochemistry on paraffin-embedded tissue.
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Liang, YY; Besch-Williford, C; et al. Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors. BREAST CANCER RESEARCH AND TREATMENT 125:407-420(2011).
Sosale, NG; Rouhiparkouhi, T; et al. Cell rigidity and shape override CD47's "sell"-signaling in phagocytosis by hyperactivating myosin-II. BLOOD 125:542-552(2015).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.