Anti-Parasite Apoptotic marker Monoclonal antibody (DMAB9287)

Mouse Anti-Parasite Apoptotic marker Monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Species Reactivity
Parasite
Immunogen
Apoptotic marker from Caenorhabditis elegans.
Conjugate
Unconjugated

Target


Alternative Names
Apoptotic Marker

Product Background


Antigen Description
Apoptosis is the fundamental process necessary for eliminating damaged or unwanted cells. Alterations in the apoptotic pathway appear to be key events in cancer development and progression. The aim of the study was to determine the p53, Bcl-2 and Bax expressions in lung cancer, taking into account histological heterogeneity and the adjacent bronchial resection margin. Tissue specimens from 60 histopathologically verified lung cancer specimens and 12 bronchial stumps were evaluated. The presence of the studied markers was revealed by immunocytochemistry on paraffin-embedded tissue.

Citations


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References


Kallergi, G; Konstantinidis, G; et al. Apoptotic Circulating Tumor Cells in Early and Metastatic Breast Cancer Patients. MOLECULAR CANCER THERAPEUTICS 12:1886-1895(2013).
Brustmann, H; et al. Expression of cellular apoptosis susceptibility protein in serous ovarian carcinoma: a clinicopathologic and immunohistochemical study. GYNECOLOGIC ONCOLOGY 92:268-276(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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