Anti-HPV type 16 Monoclonal antibody (DMAB5495)

Mouse Anti-HPV type 16 Monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
DBNWJS-2
Species Reactivity
HPV
Immunogen
BALB/C mice were immunized with recombinant HPV-16 L1 protein.
Conjugate
Unconjugated

Target


Alternative Names
HPV 16; HPV; Human papillomavirus (HPV); Papillomaviridae; Human Papilloma Virus Type 16; Human Papilloma Virus

Product Background


Antigen Description
The Papillomavirus article covers the general biological features of human and animal papillomaviruses. Human papillomavirus (HPV) is a virus from the papillomavirus family of viruses that is capable of infecting humans. Like all papillomaviruses, HPVs establish productive infections only in keratinocytes of the skin or mucous membranes. While the majority of the nearly 200 known types of HPV cause no symptoms in most people, some types can cause warts (verrucae), while others can – in a minority of cases – lead to cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and penis in men. It can also cause cancers of the head and neck (tongue, tonsils and throat). Recently, HPV has been linked with an increased risk of cardiovascular disease.

Citations


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References


Rubio, I; Seitz, H; et al. The N-terminal region of the human papillomavirus L2 protein contains overlapping binding sites for neutralizing, cross-neutralizing and non-neutralizing antibodies. VIROLOGY 409:348-359(2011).
Kawana, K; Yasugi, T; et al. Neutralizing antibodies against oncogenic human papillomavirus as a possible determinant of the fate of low-grade cervical intraepithelial neoplasia. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 296:102-105(2002).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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