Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Pathway
Gene Expression; Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing; mRNA Splicing - Major Pathway; mRNA processing;
Citations
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