Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Pathway
APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Luqmani, YA; Al Azmi, A; et al. Modification of gene expression induced by siRNA targeting of estrogen receptor a in MCF7 human breast cancer cells. INTERNATIONAL JOURNAL OF ONCOLOGY 34:231-242(2009).
Thompson, HGR; Harris, JW; et al. Identification and confirmation of a module of coexpressed genes. GENOME RESEARCH 12:1517-1522(2002).
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COA
Certificate of Analysis