Specifications
Species Reactivity
Mouse; Rat; Hamster; Human
Immunogen
Synthetic peptide corresponding to Human PSMD7 aa 55-66.Sequence: AVPFDEDDKDDS
Applications
Application Notes
ICC/IF: 5 μg/ml; IHC-P: 1 μg/ml; WB: 1 μg/ml.
Target
Alternative Names
PSMD7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7; proteasome (prosome, macropain) 26S subunit, non ATPase, 7 (Mov34 homolog); 26S proteasome non-ATPase regulatory subunit 7; MOV34; Mov34 homolog; P40; Rpn8; S12; proteasome subunit p40; 26
Product Background
Antigen Description
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Pathway
APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1;
Citations
Publication ()
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COA
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