Anti-PSMB8 polyclonal antibody (DPABH-24599)

Goat Anti-Human PSMB8 (aa 263-276) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide: C-DVSDLLHQYREANQ, corresponding to C terminal amino acids 263-276 of Human Proteasome 20S LMP7 (NP_683720.2).
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.01 - 0.03 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PSMB8; proteasome (prosome, macropain) subunit, beta type, 8; JMP; ALDD; LMP7; NKJO
Entrez Gene ID
UniProt ID

Product Background


Pathway
APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of mitotic proteins; AUF1 (hnRNP D0) destabilizes mRNA; Activation of NF-kappaB in B cells

Citations


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References


Atkinson, SP; Collin, J; et al. A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells. STEM CELLS 30:1373-1384(2012).
Nandi, D; Woodward, E; et al. Intermediates in the formation of mouse 20S proteasomes: Implications for the assembly of precursor beta subunits. EMBO JOURNAL 16:5363-5375(1997).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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