Anti-PRKAA2 polyclonal antibody (DPABH-15563)

Rabbit anti-Human PRKAA2 (aa 353-367) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Rat, Human
Immunogen
Synthetic peptide: CDDSAMHIPPGLKPHP conjugated to KLH, corresponding to amino acids 353-367 of Human AMPK alpha 2, with an N-terminal cysteine added for conjugation.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; PRKAA; AMPKa2
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Adipocytokine signaling pathway; Circadian rhythm

Citations


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References


Shah, M; Kola, B; et al. AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass. BONE 47:309-319(2010).
Fraser, S; Mount, P; et al. Regulation of the energy sensor AMP-activated protein kinase in the kidney by dietary salt intake and osmolality. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 288:F578-F586(2005).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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