Anti-PRKAA2 polyclonal antibody (DPABH-15563)

Rabbit anti-Human PRKAA2 (aa 353-367) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Rat, Human
Immunogen
Synthetic peptide: CDDSAMHIPPGLKPHP conjugated to KLH, corresponding to amino acids 353-367 of Human AMPK alpha 2, with an N-terminal cysteine added for conjugation.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; PRKAA; AMPKa2
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Adipocytokine signaling pathway; Circadian rhythm

Citations


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References


Cheung, PCF; Salt, IP; et al. Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. BIOCHEMICAL JOURNAL 346:659-669(2000).
Dyck, JRB; Kudo, N; et al. Phosphorylation control of cardiac acetyl-CoA carboxylase by cAMP-dependent protein kinase and 5 '-AMP activated protein kinase. EUROPEAN JOURNAL OF BIOCHEMISTRY 262:184-190(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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