Anti-PRKAA2 polyclonal antibody (DPABH-20989)

Goat anti-Human PRKAA2 (aa 382-392) polyclonal antibody for WB, sELISA Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: CPLDALNTTKP, corresponding to internal sequence amino acids 382-392 of Human AMPK alpha 2 (NP_006243.2)
Conjugate
Unconjugated

Applications


Application Notes
WB: 0.3 - 1μg/ml; Sandwich ELISA: 1.5 - 3μg/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; AMPK; AMPK2; PRKAA; AMPKa2
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Adipocytokine signaling pathway; Circadian rhythm

Citations


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References


Cheung, PCF; Salt, IP; et al. Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding. BIOCHEMICAL JOURNAL 346:659-669(2000).
Xavier, GD; Leclerc, I; et al. Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97:4023-4028(2000).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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