Anti-PQBP1 (aa 184-265) polyclonal antibody

Species Reactivity

Human

Immunogen

PQBP1 (NP_005701, 184 a.a. ~ 265 a.a) partial recombinant protein with GST tag. The sequence is LAPYPKSKKAVSRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQR PYPSPGAVLRANAEASRTKQQD

Conjugate

Alternative Names

PQBP1; polyglutamine binding protein 1; SHS; MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; polyglutamine-binding protein 1; polyglutamine tract-binding protein 1; nuclear protein containing WW domain 38 kD; 38 kDa nuclear protein containing a WW domain; mental

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]

Pathway

Spliceosome; Spliceosome, Prp19/CDC5L complex;