General Notes
This product (Catalog No. DPABH-09896) is a rabbit-derived polyclonal antibody raised against human PPP1R17, targeting the amino acid region 1–155 of the protein. This antibody exhibits cross-reactivity with Human PPP1R17 from mouse and rat. It has been affinity purified by Protein A. PPP1R17, an endogenous substrate for cGMP-dependent protein kinase, exists almost exclusively in cerebellar Purkinje cells, where it is possibly involved in the induction of long-term depression (PMID: 10051666). PPP1R17 inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes. Allelic variants increase susceptibility to hypercholesterolemia (PMID: 12955585).
DPABH-09896 is suitable for use in Western blot (WB) (1:5,000–1:50,000), IHC (1:200–1:800), IF/ICC (1:200–1:800) applications.
DPABH-09896 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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