General Notes
This product (Catalog No. DPABH-08354) is a rabbit-derived polyclonal antibody raised against human PPOX. This antibody exhibits cross-reactivity with PPOX from mouse. It has been affinity purified by Protein A. This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
DPABH-08354 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:50–1:200) applications.
DPABH-08354 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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