Specifications
Immunogen
Recombinant fragment corresponding to Human Oct4 aa 81-164.Sequence: WFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYG SPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Applications
Application Notes
Sandwich ELISA: 5 μg/ml; WB: 1 - 5 μg/ml.
Target
Alternative Names
POU5F1; POU class 5 homeobox 1; OTF3, POU domain class 5, transcription factor 1; POU domain, class 5, transcription factor 1; MGC22487; OCT3; Oct4; octamer-binding protein 3; octamer-binding protein 4; POU domain transcription factor OCT4; octamer-bindi
Product Background
Antigen Description
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Pathway
HIF-2-alpha transcription factor network, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem;
Citations
Publication ()
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COA
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