Anti-POU4F1 monoclonal antibody, clone FQ2083Z

Antibody Isotype

IgG

Clone

FQ2083Z

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide from the C terminal region of Human BRN3A

Conjugate

Application Notes

WB: 1/500 - 1/1000; IHC-P: 1/100 - 1/250; ICC/IF: 1/100 - 1/250; Flow Cyt: 1/90; IP: 1/50;

Alternative Names

POU4F1; POU class 4 homeobox 1; BRN3A, POU domain class 4, transcription factor 1; POU domain, class 4, transcription factor 1; RDC 1; brain-3A; homeobox/POU domain protein RDC-1; brain-specific homeobox/POU domain protein 3A; BRN3A; RDC-1; Oct-T1; brn-3

Entrez Gene ID

UniProt ID

Antigen Description

Brn3a (Brain-specific homeobox/POU domain protein 3A) is a transcription factor specifically expressed in cells of the developing mammalian nervous system. Brn3a is implicated in the regulation of specific gene expression within a subset of neuronal lineages and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Brn3a is expressed in enbryonic brain, peripheral sensory nervous system and retina. In the adult nervous system Brn3a is primarily found in the CNS: medial habenula, superficial gray of the superior colliculus, red nucleus, mesencephalic nucleus of the trigeminal ganglion, nucleus ambiguus, inferior olivary nucleus and peripheral sensory ganglia.

Pathway

Direct p53 effectors, organism-specific biosystem.