Anti-POLR2L monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human POLR2L is used for rabbit immunization.

Conjugate

Alternative Names

POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; polymerase (RNA) II (DNA directed) polypeptide L (7.6kD); DNA-directed RNA polymerases I, II, and III subunit RPABC5; hRPB7.6; hsRPB10b; RBP10; RPABC5; RPB7.6; RPB10beta; RPB10 homolog; RNA

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.

Pathway

Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem;