Specifications
Immunogen
Synthetic peptide corresponding to residues in the Human PLCG2 protein (UniProt ID: P16885).
Applications
Application Notes
Recommended dilution:
WB: 1:500-1:2000
IF: 1:50-1:200
Target
Alternative Names
PLCG2; phospholipase C, gamma 2 (phosphatidylinositol-specific); 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; PLC-IV; PLC-gamma-2; phospholipase C-IV; phosphoinositide phospholipase C-gamma-2; FCAS3;
Product Background
Antigen Description
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Pathway
Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem.
Citations
Publication ()
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COA
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