Anti-PI4KA polyclonal antibody (DPABH-01765)

Rabbit anti-Human PI4KA (aa 1-331) polyclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-331 of Human Phosphatidylinositol 4 kinase III alpha.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3,000; ICC/IF:1/100 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PI4KA; phosphatidylinositol 4-kinase, catalytic, alpha; PIK4CA; pi4K230; PI4K-ALPHA; phosphatidylinositol 4-kinase alpha
Entrez Gene ID
UniProt ID

Product Background


Pathway
3-phosphoinositide biosynthesis; D-myo-inositol (1,4,5)-trisphosphate biosynthesis; Inositol phosphate metabolism; Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Citations


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References


Stevenson, JM; Perera, IY; et al. A phosphatidylinositol 4-kinase pleckstrin homology domain that binds phosphatidylinositol 4-monophosphate. JOURNAL OF BIOLOGICAL CHEMISTRY 273:22761-22767(1998).
Szentpetery, Z; Szakacs, G; et al. Genetic and functional studies of phosphatidyl-inositol 4-kinase type III alpha. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1811:476-483(2011).

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