Specifications
Immunogen
PHLDA2 (NP_003302, 1 a.a.~111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
Application Notes
WB: 1:500-1000
Target
Alternative Names
PHLDA2; pleckstrin homology-like domain, family A, member 2; TSSC3, tumor suppressing subtransferable candidate 3; pleckstrin homology-like domain family A member 2; BWR1C; HLDA2; IPL; p17-BWR1C; tumor-supressing STF cDNA 3; p17-Beckwith-Wiedemann region
Product Background
Antigen Description
This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.
Citations
Publication ()
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COA
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