This product (Catalog No. DPABH-21082) is a rabbit-derived polyclonal antibody raised against human PEMT. This antibody exhibits cross-reactivity with PEMT from mouse. It has been affinity purified by Protein A. Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. DPABH-21082 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:50–1:300) applications. DPABH-21082 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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