Anti-PELI3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PELI3 is used for rabbit immunization.

Conjugate

Alternative Names

PELI3; pellino E3 ubiquitin protein ligase family member 3; pellino homolog 3 (Drosophila); E3 ubiquitin-protein ligase pellino homolog 3; MGC35521; pellino homolog 3; protein pellino homolog 3;

Entrez Gene ID

UniProt ID

Antigen Description

Toll-like receptors (TLRs; see MIM 603030) and IL1R (IL1R1; MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).

Pathway

Activated TLR4 signalling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IRAK1 recruits IKK complex, organism-specific biosystem; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem.