Specifications
Species Reactivity
Mouse; Rat
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PDK3 aa 250-350. The exact sequence is proprietary.Database link: Q15120
Applications
Application Notes
WB: 1/1000 - 1/2000; Flow Cyt: 1/400;
Target
Alternative Names
PDK3; pyruvate dehydrogenase kinase, isozyme 3; pyruvate dehydrogenase kinase, isoenzyme 3; pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial;
Product Background
Antigen Description
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Pathway
Metabolism, organism-specific biosystem; Pyruvate metabolism, organism-specific biosystem; Pyruvate metabolism and Citric Acid (TCA) cycle, organism-specific biosystem; Regulation of pyruvate dehydrogenase (PDH) complex, organism-specific biosystem; TCA Cycle, organism-specific biosystem; The citric acid (TCA) cycle and respiratory electron transport, organism-specific biosystem;
Citations
Publication ()
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COA
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