Specifications
Immunogen
Recombinant full length Human ERp72 protein produced in HEK293T cells (NP_004902).
Applications
Application Notes
WB: 1/2000; Flow Cyt: 1/100;
Target
Alternative Names
PDIA4; protein disulfide isomerase family A, member 4; protein disulfide isomerase associated 4; protein disulfide-isomerase A4; ERP70; ERP72; ER protein 70; ER protein 72; protein disulfide isomerase-associated 4; endoplasmic reticulum resident protein 7
Product Background
Antigen Description
The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Pathway
Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Vibrio cholerae infection, organism-specific biosystem; Vibrio cholerae infection, conserved biosystem.
Citations
Publication ()
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COA
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