Anti-PDGFRB polyclonal antibody (DPABH-24821)

Rabbit Anti-Human PDGFRB (aa 750-850) polyclonal antibody for IHC-P, ICC/IF, WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 750 - 850 of Human PDGF Receptor beta.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 0.05 μg/ml; ICC/IF: 5 μg/ml; WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PDGFRB; platelet-derived growth factor receptor, beta polypeptide; IMF1; IBGC4; JTK12; PDGFR
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Calcium signaling pathway; Cytokine-cytokine receptor interaction; DAP12 interactions

Citations


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References


Chen, GL; Arai, S; et al. A phase 1 study of imatinib for corticosteroid-dependent/refractory chronic graft-versus-host disease: response does not correlate with anti-PDGFRA antibodies. BLOOD 118:4070-4078(2011).
Tamborini, E; Virdis, E; et al. Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas(dagger). NEURO-ONCOLOGY 12:776-789(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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