Anti-Ommata Synaptic Vesicles monoclonal antibody (DMAB9277)

Mouse anti-Ommata Synaptic Vesicles monoclonal antibody for IHC, IP, WB, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
SV2
Species Reactivity
N/A
Immunogen
synaptic vesicles origin in ommata electric organ.
Conjugate
Unconjugated

Target


Alternative Names
synaptic vesicles; neurotransmitter vesicles

Product Background


Antigen Description
In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for propagating nerve impulses between neurons and are constantly recreated by the cell. The area in the axon that holds groups of vesicles is an axon terminal or "bouton". Up to 130 vesicles can be released per bouton over a ten-minute period of stimulation at 0. 2 Hz. In the human brain region V1 synaptic vesicles have an average diameter of 39. 5 nanometers with a standard deviation of 5. 1 nanometers.

Citations


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References


Besse, F; Mertel, S; et al. The Ig cell adhesion molecule Basigin controls compartmentalization and vesicle release at Drosophila melanogaster synapses. JOURNAL OF CELL BIOLOGY 177:843-855(2007).
Nishiki, T; Nihonmatsu, I; et al. Distribution of soluble N-ethylmaleimide fusion protein attachment proteins (SNAPs) in the rat nervous system. NEUROSCIENCE 107:363-371(2001).

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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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