General Notes
This product (Catalog No. DPABH-08815) is a rabbit-derived polyclonal antibody raised against human OR51L1. It has been affinity purified by Protein A. OR51L1 is a protein-coding gene located on the short arm of human chromosome 11 at position 11p15.4, encoding the olfactory receptor 51L1 protein, a member of the G-protein-coupled receptor 1 family with a characteristic seven-transmembrane domain structure. This receptor is primarily expressed in the olfactory epithelium of the nasal cavity, where it functions to detect and bind specific odorant molecules, initiating a G-protein-mediated signal transduction pathway that triggers neuronal responses essential for the sensory perception of smell. As part of the largest multigene family in the human genome—comprising over 300 intact olfactory receptor genes clustered across multiple chromosomal loci—OR51L1 contributes to the diverse repertoire of odor detection, sharing the compact structure typical of the family. While its core role is in olfaction, expression has also been noted in non-olfactory tissues such as the colonic epithelium and prostate gland, suggesting potential broader physiological functions, though these remain less characterized. Genetic variants in OR51L1 have been associated with hemolytic parameters in sickle cell anemia, but no direct causative links to major diseases have been established.
DPABH-08815 is suitable for use in WB 1 (500-1:2000), IHC 1 (50-1:200) applications.
DPABH-08815 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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