Human Anti- Neurones Heterohybridoma [NI12] (CSC-H0409)

This hybridoma produces mAbs (IgM) against Neurones

General Information


Immunogen
None
Isotype
lgM
Fusion Species
Human X Mouse Heterohybridoma
Immunological Donor
Human circulating B lymphocytes
Myeloma
NS0
Clone
NI12
Cell Line Description
Human circulating B lymphocytes transformed with EBV. It was derived from cell line 154 described in the reference given. No exogenous immunogen applied, antibody production was spontaneous.
Morphology
Lymphoblast
Growth Properties
Suspension

Culture Method


Complete Growth Medium
RPMI 1640 with 2 mM glutamine, supplemented with 10%(v/v) FBS
Subculturing
Incubate cells at 37°C with 5% CO2 in air atmosphere and maintain cultures between 3-9x10^5 cells/ml.
Storage
Liquid nitrogen vapor phase.

Target


Introduction
A neuron also known as a neurone or nerve cell is an electrically excitable cell that processes and transmits information by electrical and chemical signaling. Chemical signaling occurs via synapses, specialized connections with other cells. Neurons connect to each other to form neural networks. Neurons are the core components of the nervous system, which includes the brain, spinal cord, and peripheral ganglia. A number of specialized types of neurons exist: sensory neurons respond to touch, sound, light and numerous other stimuli affecting cells of the sensory organs that then send signals to the spinal cord and brain. Motor neurons receive signals from the brain and spinal cord, cause muscle contractions, and affect glands. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord.

Citations


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