Immunogen
Synthetic peptide corresponding to residues near the C terminal of human neurotrophic tyrosine kinase, receptor, type 1
General Notes
This product (Catalog No. DPABH-01340) is a rabbit-derived IgG polyclonal antibody raised against human NTRK1. It has been affinity purified by protein A. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
DPABH-01340 is suitable for use in IHC (1:100–1:300) application.
DPABH-01340 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
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