Synthetic peptide: C-HRELREDSIRSHFS (with a Cysteine residue linker), corresponding to C terminal amino acids 526-539 of the cytoplasmic domain of Human Natriuretic Peptide Receptor C (NP_000899.1).
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
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