Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/100 - 1/500;
Target
Alternative Names
NPR2; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); acromesomelic dysplasia, Maroteaux type , AMDM, ANPRB, NPRB; atrial natriuretic peptide receptor 2; ANPb; GUCY2B; GC-B; ANP-B; NPR-B; ANPR-B; guanylate cyclase
Product Background
Antigen Description
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Pathway
Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem;
Citations
Publication ()
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COA
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