Synthetic peptide within Human Nephrin aa 1229-1241 (C terminal). The exact sequence is proprietary. (NP_004637)Sequence: PDSLPFELRGHLV Database link: O60500
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
Pathway
Cell-Cell communication; Nephrin/Neph1 signaling in the kidney podocyte;
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