Rabbit Anti-Human NPBWR2 (a.a. 1-211) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant human NPBWR2 protein; Source: E. coli derived, PET30a; Tag: 6*His; Domain: 1-211 aa of BC067481

Conjugate

Application Notes

IHC: 1:50-1:500

General Notes

This product (Catalog No. DPABH-25524) is a rabbit-derived polyclonal antibody raised against human NPBWR2, targeting the amino acid region 1–211 of the protein. It has been affinity purified by Protein A. NPBWR1 (GPR7) and NPBWR2 (GPR8) are two structurally related G-protein coupled receptors. These two receptors share high sequence identity to each other and significant similarity with opioid and somatostatin receptors (PMID: 10407191). Neuropeptide B (NPB) and neuropeptide W (NPW) are endogenous peptide ligands of these receptors. NPBWR1 was found highly conserved in both human and rodents while NPBWR2 gene was not found in the rodent genomes (PMID: 7590751; 10407191). NPBWR1 and NPBWR2 are implicated in energy homeostasis, pain, and emotion (PMID: 23515889).
DPABH-25524 is suitable for use in IHC (1:50–1:500) application.
DPABH-25524 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

G protein coupled receptor 8; GPR8; neuropeptides B/W receptor 2; NPBWR2

Entrez Gene ID

UniProt ID