NNMT (Nicotinamide N-Methyltransferase) is a Protein Coding gene. Diseases associated with NNMT include parkinson disease, late-onset. Among its related pathways are Metabolism and Phase II conjugation. GO annotations related to this gene include methyltransferase activity and nicotinamide N-methyltransferase activity. An important paralog of this gene is PNMT. N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. Nicotinamide N-methyltransferase is an enzyme that in humans is encoded by the NNMT gene. 0The function about NNMT antigen include methyltransferase activity; nicotinamide N-methyltransferase activity; transferase activity.
Biological oxidations, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Methylation, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Phase II conjugation, organism-specific biosystem.