Specifications
Immunogen
Synthetic peptide corresponding to residues in Human IKB epsilon. (Uniprot: O00221)
Applications
Application Notes
WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250; ICC: 1/100 - 1/250;
Target
Alternative Names
NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; NF-kappa-B inhibitor epsilon; IKBE; ikB-E; ikB-epsilon; NF-kappa-BIE; ikappaBepsilon; I-kappa-B-epsilon;
Product Background
Antigen Description
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Pathway
Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Apoptosis, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem;
Citations
Publication ()
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COA
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