Three synthetic peptides conjugated to KLH, corresponding to different regions of the 68kDa Neurofilament gene product, but shared between the Human (P07196) and Mouse (P08551) protein sequences.
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
Pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events; Amyotrophic lateral sclerosis (ALS); CREB phosphorylation through the activation of CaMKII; Neuronal System
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