Anti-NDUFS3 monoclonal antibody (DCABH-260)

Mouse anti-Human NDUFS3 monoclonal antibody for IHC-G, FC, ICC/IF, IHC-P, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4G0EE3
Species Reactivity
Mouse, Rat, Cow, Human, Zebrafish
Immunogen
Whole mitochondria from Human Heart.
Conjugate
Unconjugated

Applications


Application Notes
IHC-Glut: 1/100; Flow Cyt: 1 μg/ml; ICC/IF: 5 - 10 μg/ml; IHC-P: 1/100 - 1/1000; WB: 0.5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 3 (30kD) (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; CI 30; comp
Entrez Gene ID
UniProt ID

Product Background


Pathway
3-phosphoinositide degradation, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem;

Citations


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References


Rendon, OZ; Shoubridge, EA; et al. Early complex I assembly defects result in rapid turnover of the ND1 subunit. HUMAN MOLECULAR GENETICS 21:3815-3824(2012).
Vogel, RO; Dieteren, CEJ; et al. Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits. JOURNAL OF BIOLOGICAL CHEMISTRY 282:7582-7590(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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