Full length protein corresponding to Human HEC1 aa 1-642.
Sequence:
MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKPTS ERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLC EFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEE VPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVA
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
NDC80; NDC80 kinetochore complex component; HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80; kinetochore protein NDC80 homolog; kinetochore associated 2; kinetochore protein Hec1; kinetochore-associated protein 2; highly expressed in cancer protein; retinoblastom
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Pathway
Aurora B signaling; Cell Cycle, Mitotic; Mitotic Anaphase; Mitotic Prometaphase
Citations
Publication ()
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COA
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