Anti-Myelin monoclonal antibody (DMAB14435)

Mouse anti-Human Myelin monoclonal antibody for IHC Datasheet

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Host Species
Antibody Isotype
Species Reactivity
Native purified human Myelin.


Application Notes
Immunohistochemistry (1:10) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.


Alternative Names
MOG; MOG IG 2; Myelin oligodendrocyte glycoprotein CD34(Endothelial Cell Marker); Anti-Myelin Mab; Mouse Anti-Human Myelin Monoclonal Antibody

Product Background

Antigen Description
Myelin is a dielectric (electrically insulating) material that forms a layer, the myelin sheath, usually around only the axon of a neuron. It is essential for the proper functioning of the nervous system. Myelin is an outgrowth of a type of glial cell. The production of the myelin sheath is called myelination. In humans, the production of myelin begins in the fourteenth week of fetal development, although little myelin exists in the brain at the time of birth. During infancy, myelination occurs quickly and continues through the adolescent stages of life.


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Stathopoulos, P; Alexopoulos, H; et al. Autoimmune antigenic targets at the node of Ranvier in demyelinating disorders. NATURE REVIEWS NEUROLOGY 11:-(2015).
Okumura, A; Nakazawa, M; et al. Anti-aquaporin 4 antibody-positive acute disseminated encephalomyelitis. BRAIN & DEVELOPMENT 37:339-343(2015).

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