Specifications
Immunogen
A fusion protein containing the E. coli maltose binding protein and a fragment of the mouse bcrp protein corresponding to amino acids 221-394.
Applications
Application Notes
ICC: 1/20 - 1/50; IHC-Fr: 1/20; WB: 1/20 - 1/50;
Target
Alternative Names
ABCG2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette sub-family G member 2; ABC15; ABCG 2; ABCG2; ABCG2_HUMAN; ABCP; ATP-binding cassette sub-family G member 2; BCRP1; BMDP; Breast cancer resistance protein; CD338; CDw338; CDw
Product Background
Antigen Description
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Irinotecan Pathway, organism-specific biosystem;
Citations
Publication ()
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