Anti-MDV Monoclonal antibody (DMAB3906)

Mouse anti MDV monoclonal antibdoy for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
C154M
Species Reactivity
MDV
Immunogen
MDV Strains SB-1 and Rispens
Conjugate
Unconjugated

Target


Alternative Names
Gallidherpesvirus 3; Gallidherpesvirus type 3; Marek"s disease herpesvirus 2; Marek"s disease virus type 2; MDV; Marek Disease Virus

Product Background


Antigen Description
Marek's Disease Virus, (MDV), is an oncogenic avian doublestranded DNA herpesvirus. It is highly contagious and results in aggressive T-cell lymphomas. Infection of MDV occurs via the respiratory tract, whereits uptake by macrophages and dendritic cells allows it to be transported inthe bloodstream to visceral organs and peripheral nerves, causing death in upto 80 percent of birds. It occurs in two main forms, depending on which partsof the body are affected by the tumours. In the nervous form the nerves,particulary the sciatic nerves, are affected. In the visceral form,greyish-white tumours are found in the ovaries, liver, spleen, kidney, heartand other organs. Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer foruse in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Citations


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References


Islam, AFMF; Walkden-Brown, SW; et al. Effects of vaccine dose, virus challenge dose and interval from vaccination to challenge on protection of broiler chickens against Marek's disease virus challenge. AUSTRALIAN VETERINARY JOURNAL 85:348-355(2007).
Markowski-Grimsrud, CJ; Schat, KA; et al. Infection with chicken anaemia virus impairs the generation of pathogen-specific cytotoxic T lymphocytes. IMMUNOLOGY 109:283-294(2003).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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