Fusion protein containing the C-terminal region of Human MYLIP with proprietary tag.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/5000.
Target
Alternative Names
MYLIP; myosin regulatory light chain interacting protein; E3 ubiquitin-protein ligase MYLIP; E3 ubiquitin ligase inducible degrader of the low density lipoprotein receptor; IDOL; MIR; band 4.1 superfamily member BZF1; inducible degrader of the LDL-recepto
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Citations
Publication ()
Have you cited DPABH-25825 in a publication? Let us know and earn a reward for your research.
My Review for Anti-MYLIP (C-terminal) polyclonal antibody
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
