Specifications
Immunogen
Recombinant protein corresponding to human MYL2.
Applications
Application Notes
ELISA (1:10000); WB (1:500-1:2000) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
MYL2; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; cardiac ventricular myosin light chain 2; CMH10; MLC-2; MLC-2v; RLC of myo
Product Background
Antigen Description
Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Pathway
CDC42 signaling events, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Citations
Publication ()
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COA
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